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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Unequal crossing over ： ウィキペディア英語版 Unequal crossing over ''Unequal crossing over'' is a type of gene duplication or deletion event that deletes a sequence in one strand and replaces it with a duplication from its sister chromatid in mitosis or from its homologous chromosome during meiosis. It is a type of chromosomal crossover between homologous sequences that are not paired precisely. Normally genes are responsible for occurrence of crossing over. It exchanges sequences of different links between chromosomes. Along with gene conversion, it is believed to be the main driver for the generation of gene duplications and is a source of mutation in the genome. ==Mechanisms== During meiosis, the duplicated chromosomes in eukaryotic organisms attach to each other in the centromere region and pair to each other (chromatids). The maternal and paternal chromosomes then align alongside each other. During this time, recombination can take place via crossing over of sections of the paternal and maternal chromatids and leads to reciprocal recombination or non-reciprocal recombination.〔 Unequal crossing over requires a measure of similarity between the sequences for misalignment to occur. The more similarity within the sequences, the more likely unequal crossing over will occur.〔 One of the sequences is thus lost and replaced with the duplication of another sequence. When two sequences are misaligned, unequal crossing over may create a tandem repeat on one chromosome and a deletion on the other. The rate of unequal crossing over will increase with the number of repeated sequences around the duplication. This is because these repeated sequences will pair together, allowing for the mismatch in the cross over point to occur. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Unequal crossing over」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.